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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SQSTM1
All Species:
17.58
Human Site:
S49
Identified Species:
42.96
UniProt:
Q13501
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13501
NP_001135771.1
440
47687
S49
G
P
C
E
R
L
L
S
R
V
A
A
L
F
P
Chimpanzee
Pan troglodytes
XP_518154
440
47713
S49
G
P
C
E
R
L
L
S
R
V
A
A
L
F
P
Rhesus Macaque
Macaca mulatta
XP_001102347
439
47572
S49
G
P
C
E
R
L
L
S
R
V
A
A
L
F
P
Dog
Lupus familis
XP_538580
688
72696
A125
R
P
V
D
T
L
L
A
L
F
S
S
L
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q64337
442
48144
S49
G
P
C
E
R
L
L
S
R
V
A
V
L
F
P
Rat
Rattus norvegicus
O08623
439
47663
S47
G
P
C
E
R
L
L
S
R
V
A
V
L
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506086
492
54053
R90
G
C
C
D
R
L
L
R
R
L
D
Q
V
F
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P14199
599
65285
Q69
D
E
I
E
I
V
N
Q
N
D
Y
E
I
F
L
Honey Bee
Apis mellifera
XP_392222
399
45715
H46
E
L
F
P
E
L
N
H
K
S
F
T
I
S
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795534
414
45119
P49
V
F
P
S
L
G
D
P
D
Y
F
S
L
S
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.7
49.7
N.A.
90.7
91.3
N.A.
59.9
N.A.
N.A.
N.A.
N.A.
21.3
22.9
N.A.
30.6
Protein Similarity:
100
99.7
98.8
54.5
N.A.
94.3
94.5
N.A.
70.5
N.A.
N.A.
N.A.
N.A.
35.2
43.4
N.A.
42.5
P-Site Identity:
100
100
100
33.3
N.A.
93.3
93.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
60
N.A.
93.3
93.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
50
30
0
0
0
% A
% Cys:
0
10
60
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
0
20
0
0
10
0
10
10
10
0
0
0
0
% D
% Glu:
10
10
0
60
10
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
10
10
0
0
0
0
0
0
10
20
0
0
70
0
% F
% Gly:
60
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
80
70
0
10
10
0
0
70
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
0
10
0
0
0
0
0
0
% N
% Pro:
0
60
10
10
0
0
0
10
0
0
0
0
0
0
70
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% Q
% Arg:
10
0
0
0
60
0
0
10
60
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
50
0
10
10
20
0
20
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% T
% Val:
10
0
10
0
0
10
0
0
0
50
0
20
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _